The Latest in Depression Treatment: TMS for Depression TMS or transcranial magnetic stimulation treatment is a non-invasive, FDA-approved therapy for depression. Find out what TMS is and how TMS for depression works. Article Contents What Is Depression? Many people are considering TMS for depression. Major depressive disorder (MDD) is a mental health diagnosis that requires medical care. With treatment, patients diagnosed with depression can receive significant symptom relief. Screening and early detection are critical components of treatment for MDD. Treatment plans often include medication,